When someone just begins learning to play a musical instrument, they spend a lot of time doing scale exercises. They practice ascending from the lowest note to the highest note and descending back from highest to lowest. The exercises help budding musicians learn the proper ways to use their instruments.
It can happen after only a few minutes of conversation with someone. Your stomach clenches, your heart rate might accelerate, and you start to fidget. You feel uncomfortable and want to escape the conversation. So do you have food poisoning? Nope, worse. You have a core values mismatch.